When Does Meiosis 2 Occur In Females

The process of meiosis is a crucial part of sexual reproduction, allowing the formation of gametes with half the genetic material of the parent cell. Meiosis consists of two divisions, aptly named Meiosis I and Meiosis II. While Meiosis I is responsible for reducing the chromosome number by half, the purpose of Meiosis II is to separate the sister chromatids produced during Meiosis I. This process occurs in both males and females, but the timing differs between the two genders.

**When does Meiosis II occur in females?**

Meiosis II in females occurs after fertilization when the secondary oocyte, which is the result of Meiosis I, is triggered to complete the second division. Meiosis I in females begins during fetal development, but it halts in the prophase stage and resumes only after puberty. This pause in Meiosis I is essential because it ensures that the eggs are at the optimal stage of development at the time of fertilization.

Now that we understand the basic concept of Meiosis II in females, let’s delve deeper and explore the different stages and factors that influence the timing of this crucial event.

1. The stages of Meiosis II in females

Meiosis II in females consists of four stages: Prophase II, Metaphase II, Anaphase II, and Telophase II. Here’s a breakdown of each stage:

Prophase II:

During Prophase II, the chromosomes condense, and the nuclear envelope begins to break down. The centrosomes, which are responsible for organizing the spindle fibers, move towards opposite poles of the cell.

Metaphase II:

In Metaphase II, the chromosomes align at the metaphase plate, a region equidistant between the two poles of the cell. Each chromosome is attached to spindle fibers originating from the centrosomes at the opposite poles.

Anaphase II:

During Anaphase II, the sister chromatids of each chromosome separate and move towards opposite poles of the cell.

Telophase II:

Telophase II marks the final stage of Meiosis II. The nuclear envelope reforms around the separated chromosomes, the spindle fibers disintegrate, and the cell eventually undergoes cytokinesis, resulting in the formation of four haploid cells called polar bodies.

2. Factors influencing the timing of Meiosis II in females

Several factors play a role in determining when Meiosis II occurs in females. Let’s take a closer look at these factors:

Hormonal regulation:

The initiation of Meiosis II in females is regulated by hormonal signals. Follicle-stimulating hormone (FSH) released by the pituitary gland stimulates the development of ovarian follicles, which house the eggs. As the follicles mature, they release increasing levels of estrogen, which signals the pituitary gland to release luteinizing hormone (LH). LH surge triggers ovulation, the release of the secondary oocyte from the follicle, and subsequently initiates Meiosis II.


In females, Meiosis II is not completed unless fertilization occurs. If fertilization doesn’t take place, Meiosis II is arrested, and the secondary oocyte degenerates. However, if fertilization occurs, certain events are triggered in the secondary oocyte to complete Meiosis II and produce a mature egg.

Age and reproductive cycle:

The timing of Meiosis II also varies based on age and the reproductive cycle of the female. Following puberty, females have a limited number of ovarian follicles, and each menstrual cycle, a group of follicles starts to mature. Among these follicles, one becomes dominant and releases the secondary oocyte for potential fertilization. If fertilization doesn’t happen, the secondary oocyte undergoes degeneration. This process repeats until menopause when the ovaries lose their ability to produce viable eggs.

External factors:

External factors such as stress, hormonal imbalances, and certain medical conditions can disrupt the timing of Meiosis II in females. These factors can interfere with the hormonal signals required for the progression of Meiosis II or disrupt the maturation and release of a healthy secondary oocyte.

Frequently Asked Questions

Q: Can Meiosis II occur in females without fertilization?

Yes, Meiosis II can occur in females without fertilization, but the process is arrested and the secondary oocyte degenerates. Meiosis II can only be completed if fertilization takes place.

Q: What happens to the polar bodies produced during Meiosis II in females?

The polar bodies, also known as non-functional eggs, produced during Meiosis II in females generally degenerate and do not participate in fertilization. They play a supportive role by providing nutrients to the developing egg before disintegrating.

Q: Is the timing of Meiosis II the same in all females?

No, the timing of Meiosis II can vary among females due to hormonal differences, reproductive cycle variations, and external factors. Factors such as age, overall health, and environmental influences can affect the timing of Meiosis II.

Final Thoughts

Meiosis II in females is an intricate process that occurs after fertilization, allowing the completion of the second division and the production of mature eggs. Hormonal regulation, the occurrence of fertilization, age, and reproductive cycle all play a role in determining the timing of Meiosis II. Understanding the intricacies of this process not only sheds light on the complexity of reproduction but also highlights the delicate balance of factors required for successful fertilization and the formation of healthy offspring.

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