|
Normal peak estradiol concentrations (pg/ml) on the hCG day
|
|
| Variable (means±S.E.M.) |
500–1000 |
1001–2000 |
2001–3000 |
3001–4000 |
P value |
|
| No. of women |
61 |
53 |
41 |
45 |
|
| Age (years) |
36.95±3.73 |
35.3 ± 5.06 |
33.8 ± 3.93 |
33.4 ± 5.07 |
0.01 |
| Body mass index (kg/m2) |
22.7 ± 3.04 |
23.4 ± 3.65 |
24.8 ± 5.63 |
22.32 ± 2.8 |
NS |
| Leptin (on the HCG day; ng/ml) |
57.14 ± 7.9d |
46.5 ± 8.4a |
66.7 ± 8.4h |
60.3 ± 5.8c |
0.03 |
| No. of rFSH ampoules |
35.44 ± 2.82 |
28.3 ± 2.41 |
29.1 ± 4.19 |
18.77 ± 1.89 |
NS |
| Stimulation days |
6.61 ± 0.36 |
6.26 ± 0.35 |
6.00 ± 0.47 |
5 ± 0.31 |
NS |
| No. of retrieved oocytes |
3.74 ± 1.94 |
6.43 ± 2.61 |
8.54 ± 4.13 |
9.03 ± 4.4 |
<0.001 |
| Phase II oocytes |
2.81 ± 0.38 |
5.75 ± 0.36 |
8.36 ± 1.39 |
8.77 ± 1.67 |
<0.001 |
| No. of transferred embryos |
1.96 ± 1.07 (n = 120) |
3.94 ± 1.53 (n = 209) |
4.07 ± 1.72 (n = 167) |
3.94 ± 1.41 (n = 178) |
<0.001 |
| Embryo quality |
Grade A with  5 blastomeres |
1 ± 0.26 |
1.93 ± 0.34 |
2.18 ± 0.63 |
2.65 ± 0.45 |
<0.001 |
| Grade B with 5 blastomeres |
0.14 ± 0.007n |
0.97 ± 0.21k |
0.55 ± 0.21l |
0.11 ± 0.11m |
<0.05 |
| Grade A with <5 blastomeres |
0.41 ± 0.13 |
0.14 ± 0.006 |
0.73 ± 0.38 |
0.71 ± 0.52 |
NS |
| Grade B with <5 blastomeres |
0.41 ± 0.13n |
0.93 ± 0.27k |
0.64 ± 0.28l |
0.53 ± 0.31m |
<0.05 |
| Good embryo quality |
58.4%h |
73.6%e |
64.6% |
70% |
NS |
| Poor embryo quality |
31.2%s |
12.4%p |
25.7%q |
28.4%r |
NS |
|
|
| P values among the four groups was estimated with the Kruskal–Wallis test. Superscript letters: a was significantly lower (P < 0.05) than b, c and d, and k was significantly higher (P < 0.05) than l, m and n with the Mann–Whitney test. |
For embryo quality, e was significantly higher (P < 0.05) than h, and p was significantly lower (P < 0.05) than q, r and s with the  2 test. NS, not significant. |
