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Implantation, deciduoma formation and live births in mast cell-deficient mice (W/W^v)

Summary. The intraluminal injection of oil produced deciduoma formation in ovariectomized, mast cell-normal (+ /+) and mast cell-deficient (W/W^v) mice that were treated with exogenous steroids. Oil injection and trauma (e.g. sutures) also produced a deciduoma in ovariectomized + / + and W/W^v mice that had received a single control (+ / +) ovary transplanted under the kidney capsule. After transfers of donor blastocysts, implantation and live births were obtained in +/+ and W/W^v mice containing a single ovary transplant. Our results demonstate that uterine mast cells are not required for the production of a decidual cell response, implantation, gestation or the birth of live offspring in mice.

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