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Modification of the embryo–maternal relationship in ewes by progesterone treatment early in the oestrous cycle

Summary. When 25 mg progesterone/day were injected into ewes on Days 0–3 of the oestrous cycle, (i) the subsequent cycle was shortened by 4 days and (ii) on Day 6 such ewes provided an acceptable uterine environment for the survival of 10-day-old embryos. We suggest that exposure of the non-pregnant uterus to approximately 8 days of normal luteal concentrations of progesterone may be necessary to initiate luteolysis.

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				S. Z. El-Zarkouny, J. A. Cartmill, B. A. Hensley, and J. S. Stevenson Pregnancy in Dairy Cows After Synchronized Ovulation Regimens With or Without Presynchronization and Progesterone J Dairy Sci, April 1, 2004; 87(4): 1024 - 1037. [Abstract] [Full Text] [PDF]