Reproduction   citetrack
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS  
Journal of Reproduction and Fertility (1981) 61 59-64
DOI: 10.1530/jrf.0.0610059
Copyright © 1981 Society for Reproduction and Fertility
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hinton, B. T.
Right arrow Articles by Setchell, B. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hinton, B. T.
Right arrow Articles by Setchell, B. P.

Effects of carnitine and some related compounds on the motility of rat spermatozoa from the caput epididymidis

B. T. Hinton, D. E. Brooks, H. M. Dott and B. P. Setchell

Summary. Spermatozoa were collected from the rat caput epididymidis by micropuncture and their motility assessed after dilution in physiological saline containing carnitine or related compounds. L(+)-Carnitine caused, 2 min after dilution, a transient stimulation of the motility of spermatozoa with low initial motility. No stimulatory effects were seen on spermatozoa which had high initial motility. The D-isomer inhibited the motility of spermatozoa with high initial motility after 2 min and all compounds tested appeared to inhibit, at 20 min after dilution, the motility of spermatozoa with high initial motility. Acetyl-L-carnitine and acetyl-D-carnitine stimulated the motility of spermatozoa with low initial motility. This study suggests that carnitine may be important in the development by spermatozoa of the potential for motility and also to maintain mature spermatozoa in a quiescent state.




This article has been cited by other articles:


Home page
 ReproductionHome page
D. Kobayashi, I. Tamai, Y. Sai, K. Yoshida, T. Wakayama, Y. Kido, J.-i. Nezu, S. Iseki, and A. Tsuji
Transport of carnitine and acetylcarnitine by carnitine/organic cation transporter (OCTN) 2 and OCTN3 into epididymal spermatozoa
Reproduction, November 1, 2007; 134(5): 651 - 658.
[Abstract] [Full Text] [PDF]

Home page
 ReproductionHome page
D. Kobayashi, M. Irokawa, T. Maeda, A. Tsuji, and I. Tamai
Carnitine/organic cation transporter OCTN2-mediated transport of carnitine in primary-cultured epididymal epithelial cells
Reproduction, December 1, 2005; 130(6): 931 - 937.
[Abstract] [Full Text] [PDF]

Home page
 ReproductionHome page
D. Kobayashi, A. Goto, T. Maeda, J.-i. Nezu, A. Tsuji, and I. Tamai
OCTN2-mediated transport of carnitine in isolated Sertoli cells
Reproduction, June 1, 2005; 129(6): 729 - 736.
[Abstract] [Full Text] [PDF]

Home page
 J. Pharmacol. Exp. Ther.Home page
V. Srikanth, T. Malini, J. Arunakaran, P. Govindarajulu, and K. Balasubramanian
Effects of Ethanol Treatment on Epididymal Secretory Products and Sperm Maturation in Albino Rats
J. Pharmacol. Exp. Ther., February 1, 1999; 288(2): 509 - 515.
[Abstract] [Full Text]

Home page
 J. Biol. Chem.Home page
I. Tamai, R. Ohashi, J.-i. Nezu, Y. Sai, D. Kobayashi, A. Oku, M. Shimane, and A. Tsuji
Molecular and Functional Characterization of Organic Cation/Carnitine Transporter Family in Mice
J. Biol. Chem., December 15, 2000; 275(51): 40064 - 40072.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS  
Copyright © 1981 by the Society for Reproduction and Fertility.