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Prostaglandin F-2 and LH release in immature ewes

Summary. The effect of PGF-2 on LH release in immature ewes was studied. One intramuscular injection of PGF-2 induced LH release 36–72 h after treatment in 3/4 ewes. The LH variations were not associated with changes in the plasma concentration of progesterone and oestrogens. These results suggest that the LH release in immature ewes is due to PGF-2 acting at central structures.