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Journal of Reproduction and Fertility (1980) 58 389-393
DOI: 10.1530/jrf.0.0580389
Copyright © 1980 Society for Reproduction and Fertility
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Immunochemical characterization and serum concentrations of pregnancy-associated serum proteins in mice

J. Hau, P. Svendsen, B. Teisner and G. Thomsen Pedersen

Summary. The glycoprotein structure of two pregnancy-associated murine proteins, {alpha}1-PAMP and {alpha}2-PAMP, was analysed by using concanavalin A (Con A) affinity electrophoresis: {alpha}1-PAMP was completely precipitated by free Con A, whereas {alpha}2-PAMP showed heterogeneity. The isoelectric points of {alpha}1-PAMP and {alpha}2-PAMP were determined at 4·2 and 4·0 respectively by using crossed immunoelectrofocusing. The {alpha}2-PAMP was detectable only in the serum of pregnant mice and fetuses. Maternal serum concentrations increased from Day 8 of pregnancy, remained at high values between Days 14 and 18, and could not be detected by 2 days post partum.






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Copyright © 1980 by the Society for Reproduction and Fertility.