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Luteotrophic effect of the rabbit blastocyst

Summary. Progesterone concentrations in peripheral plasma of 27 rabbits were determined by radioimmunoassay daily from Days 1 to 7. The rate of increase was significantly higher in pregnant than in pseudopregnant rabbits from Days 5 to 7 (P < 0·02), but not before Day 5. Transfer of Day-4 or -5 blastocysts to synchronous, pseudopregnant recipients resulted in a significant rise in progesterone levels in comparison with those in sham-operated controls (P < 0·01) or pseudopregnant does (P < 0·01).