This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Hyne, R. V. Articles by Boettcher, B. Search for Related Content PubMed Articles by Hyne, R. V. Articles by Boettcher, B.

The metabolism and motility of human spermatozoa in the presence of steroid hormones and synthetic progestagens

Summary. The metabolism and motility of human ejaculated spermatozoa incubated in vitro with steroids were studied. Progesterone and norethynodrel depressed the respiration, glycolytic metabolism and the motility of washed spermatozoa. Lynoestrenol did not affect the respiration or glycolysis of the spermatozoa, but did inhibit motility. Oestradiol did not cause any consistent alteration of the sperm metabolism, and did not affect the motility. Progesterone and norethynodrel appear to act on the plasma membrane of human spermatozoa to increase its permeability and hence to facilitate the loss of essential cofactors required for the glycolytic and oxidative processes.

This article has been cited by other articles:

				A. Junaidi, C M. Luetjens, J. Wistuba, A. Kamischke, C.-H. Yeung, M. Simoni, and E. Nieschlag Norethisterone enanthate has neither a direct effect on the testis nor on the epididymis: a study in adult male cynomolgus monkeys (Macaca fascicularis) Eur. J. Endocrinol., April 1, 2005; 152(4): 655 - 661. [Abstract] [Full Text] [PDF]

				E. Falkenstein, H.-C. Tillmann, M. Christ, M. Feuring, and M. Wehling Multiple Actions of Steroid Hormones---A Focus on Rapid, Nongenomic Effects Pharmacol. Rev., December 1, 2000; 52(4): 513 - 556. [Abstract] [Full Text] [PDF]

				A. Revelli, M. Massobrio, and J. Tesarik Nongenomic Actions of Steroid Hormones in Reproductive Tissues Endocr. Rev., February 1, 1998; 19(1): 3 - 17. [Abstract] [Full Text]