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Immunocytochemical localization of binding 'sites' for LH and hCG in preimplantation mouse embryos

Summary. By using an immunoperoxidase indirect antibody method, mouse blastocysts were found to bind specifically hCG and ovine LH but not FSH or the β unit of hCG. Brown peroxidase reaction products were present in the morula and increased with the formation of the blastocoele. The LH/hCG binding 'sites' may be related to the initiation of steroidogenesis in the embryo.