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Early effects of oil on rat uterine epithelium sensitized for decidual induction

Peanut oil injected into the uterine lumen of the rat or mouse is a well known deciduogenic stimulus (Finn & Keen, 1963; Finn & Hinchliffe, 1964, 1965). It is believed to induce a decidual reaction by a mechanism similar to that of the implanting blastocyst (Finn & Porter, 1975). This view is primarily based on the fact that the hormonal requirements for (Finn, 1965; Meyers, 1970) and the morphological changes of the stroma after (Finn & Hinchliffe, 1964, 1965) induction are similar to those for blastocyst implantation. Peanut oil has, therefore, often been used to study early decidualization (Hetherington, 1968; Miller, 1973).