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Metabolic clearance rate, production rate, and source of progesterone in donkeys with fetuses of different genotypes

Fetal genotype has a pronounced influence upon progestagen and gonadotrophin (PMSG) concentrations in the peripheral blood of mares and donkeys during the first half of pregnancy. Plasma progestagen and PMSG concentrations in donkeys carrying hinny ( horse x donkey) conceptuses are appreciably higher than in donkeys carrying normal donkey conceptuses, or in mares carrying normal horse conceptuses (Allen, 1975). In contrast, PMSG concentrations are low in mares carrying mule ( donkey x horse) conceptuses compared with mares carrying normal horse conceptuses (Bielanski, Ewy & Pigoniowa, 1956; Clegg, Cole, Howard & Pigon, 1962; Allen, 1969), although progestagen concentrations are unaffected (Allen, 1975).