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During pseudopregnancy, pregnancy and lactation in the rat there is a characteristic persistent function of the corpus luteum and an interruption of cyclic ovulation. Investigation of the response of ovarian follicles to exogenous gonadotrophins during pseudopregnancy and pregnancy in the rat has led to controversial results (Greenwald, 1966; Rees, Dieten, Bijleveld & Muller, 1968; Brown-Grant, 1969; Ying, Gove, Fang & Greep, 1973; Welschen, Osman, Dullaart, de Greef, Uilenbrock & de Jong, 1975). We therefore examined the effect of HCG on the responsiveness of follicles, their maturation and maintenance at various stages of pseudopregnancy, pregnancy and lactation in the rat.
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