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Some clinical aspects of pituitary–ovarian relationships in women with ovulatory infertility

The defective luteal phase: In the past 15 years the treatment of infertility has been affected most by progress in the induction of ovulation (Gemzell, Diczfalusy & Tillinger, 1958; Lunenfeld, Menzi & Volet, 1960; Kistner, 1975). The impact of this therapeutic advance is reflected in the diagnoses made during attendance at specialized clinics, as described by Cox (1975) and shown in Table 1, but there is still a large proportion of all patients (17·6% in Cox's study) in whom no cause can be found for their infertility.