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Selective and age-dependent changes of prostaglandin E-2 in the epididymis and vas deferens of the rat

The biosynthesis of prostaglandins (PGs) occurs in the testes and seminal vesicles of various animal species (Carpenter, Manning & Wiseman, 1971; Christ & Van Dorp, 1972; Ellis, 1972). The effects of PGs on the contractility of the testicular capsule, epididymis and vas deferens in vitro and the effects of PG administration on the transport of spermatozoa suggest a possible role of PGs in the physiology of the male reproductive system (Davis, Langford & Kirby, 1970; Hafs, Louis & Stellflung, 1974).

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