This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Finn, C. A. Articles by Bredl, J. C. S. Search for Related Content PubMed Articles by Finn, C. A. Articles by Bredl, J. C. S.

Autoradiographic study of the effect of actinomycin D on decidual differentiation of stromal cells in the mouse uterus

The administration of actinomycin D to pregnant mice before the zygote has started to implant does not prevent the early stages of the implantation reaction but does delay, for a period of about 30 h, differentiation of the endometrial stromal cells into decidual cells (Finn & Martin, 1972; Finn & Bredl, 1973). During the period of delay vascular permeability is increased and oedema fluid collects in the stroma. An inhibitory effect of actinomycin D on decidualization has also been demonstrated in the rat (Burin & Sartor, 1965; Sananès & Psychoyos, 1970).