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Endometrial blood flow in rats during early pregnancy

In the rat, total uterine blood flow is maximal during peak secretion of oestrogen (Spaziani & Suddick, 1967; Greiss & Anderson, 1973). This is probably due to a high rate of flow through the myometrium, since endometrial blood flow has been shown to be twice as high during dioestrus as during oestrus (Einer-Jensen, 1976). If the high endometrial blood flow in dioestrus is associated with progestagen secretion, a high endometrial blood flow in early pregnancy would be anticipated. This supposition was examined in the present study.