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Summary.: Cytochemical studies were carried out on normal and cryptorchid human testes in order to define the distribution of glycogen and some related enzymes during testicular maturation. The glycogen content, and phosphorylase and amylo 1-4,1-6 transglucosidase activities increased in the seminiferous tubules of scrotal testes with maturation. Weaker reactions were always obtained in cryptorchid testes. Phosphorylase and amylo 1-4,1-6 transglucosidase activities were detected in some cells in the intertubular spaces. The localization of these enzymes in scrotal and cryptorchid testes differed at different ages. It was not possible to demonstrate the presence of glycogen synthetase. The rôle played by these glycogen metabolism enzymes in the testis is discussed.
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