This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by MAIBENCO, H. C. Articles by KREHBIEL, R. H. Search for Related Content PubMed PubMed Citation Articles by MAIBENCO, H. C. Articles by KREHBIEL, R. H.

REPRODUCTIVE DECLINE IN AGED FEMALE RATS

Reproductive decline in older female rodents has been interpreted as being due to deficiencies in various segments of the reproductive tract. Previous observations, such as those of Ingram, Mandle & Zuckerman (1958), Block & Flury (1959), Finn (1962), Blaha (1964) and Conners, Thorpe & Soderwall (1970) among others, have attributed deficiencies to one or all of the reproductive organs. In the present observations of a colony of aged females, examples of deficiencies at all levels of the reproductive tract were found. There were, however, a number of these animals which did produce a normal complement of ova and which fostered their continued development.

Sixty-six virgin or multiparous rats, aged 18 months or older, were caged with males and matings were noted as having