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A number of authors (Brambell, 1927; Engle, 1931; Barraclough, 1955;Ben-Or, 1963; Peters, 1969; Byskov, Pedersen & Peters, 1970; Stegner & Onken, 1971) have described various aspects of the normal development of infantile and juvenile mouse ovaries. Pedersen (1969, 1970) examined the growth rate of mouse ovarian follicles of various sizes and the size distribution of the follicle population at 7, 14, 21, 28 and 35 days after birth. The present work is concerned with the changes between the ages of 16 and 20 days in the population of mouse ovarian follicles that have at least three layers of granulosa cells.
Foster litters of ten female CFW mice (nine sub-lines of the outbred CFW strain were obtained from the M.R.C. Laboratory Animals Centre, Carshalton, Surrey in
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