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LOCAL PRODUCTION OF PROTEIN DURING IMPLANTATION IN THE RABBIT

A gradual increase in blastokinin (BKN) concentration in the uterus of the rabbit has been noted between Days 2 to 5 (or 6) of pregnancy (Krishnan & Daniel, 1967) and pseudopregnancy (Johnson, 1972) or after progesterone administration (Arthur & Daniel, 1972). It is possible that all of the BKN-producing tissue (presumed to be the endometrim) could initiate BKN production at about the same time and accelerate it thereafter to reach a maximum level some 2 to 3 days later. A second possibility is that there is one local region that begins to secrete BKN, and this is followed by progressive expansion of the secretory areas; for example, the secreting activity might begin at the tubal end of the uterus early on Day 3 post coitum and then progress caudally