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HISTOLOGICAL AND FUNCTIONAL ANALYSIS OF THE AUTOTRANSPLANTED CORPUS LUTEUM OF PREGNANCY IN THE RAT

Summary.: A technique is described for the isolation and autotransplantation under the renal capsule of CL of pregnancy in the rat. Maintenance of exogenous progesterone, at least until placentation, ensures maintenance of normal luteal structure. The grafts do not appear to secrete oestrogen. They do secrete reduced quantities of progesterone. Early withdrawal of exogenous progesterone or later hysterectomy cause regression of the grafts. It is speculated that luteotrophic hormones act directly to maintain luteal structure and function.