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PLASMA KININ AND KININOGEN LEVELS IN WOMEN DURING PREGNANCY AND IN LABOUR

Summary.: Kininogen and kinin levels in venous plasma were determined in groups of normal adult men and women and in pregnant women at different periods of gestation and in labour.

Kininogen levels were found to be significantly higher in the pregnant women than in the male and female controls. A significant positive linear correlation was found between period of gestation and plasma kininogen level.

Differences between the mean plasma kinin levels in groups of control adults and pregnant women were in most cases not significant.

No significant linear correlation was found between kinin and kininogen levels in plasma in any of the groups studied and no definite trends were found in the kinin and kininogen levels at delivery.