This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by CHRISTENSON, C. M. Articles by ELEFTHERIOU, B. E. Search for Related Content PubMed PubMed Citation Articles by CHRISTENSON, C. M. Articles by ELEFTHERIOU, B. E.

DOSE-DEPENDENCE OF SUPEROVULATION RESPONSE IN MICE TO TWO INJECTIONS OF PMSG

Summary.: Female C57BL/6J mice were injected on Day 24 of age with one of the following doses of PMSG: 1, 2, 4, 8, 16 or 24 i.u., and again on Day 26 with an identical dose. More than 85 % of the variation of the number of ova produced between doses 1 and 16 is accounted for by its corresponding variation in dose. At 24 i.u. of PMSG, the response declined significantly.This phenomenon indicates that PMSG, an FSH-like substance, not only provides for follicular maturation but also can cause release of ova without the synergistic effect of HCG, an LH-like substance, perhaps through stimulation of the release of endogenous LH.