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Summary.: Carbon dioxide formed by the mouse oocyte from glucose was 0·145 pmol/hr/oocyte, which is the same as the value previously found for unfertilized mouse ova. Carbon dioxide formed by the Rhesus monkey oocyte from pyruvate and glucose was 12·77 and 0·73 pmol/hr/oocyte, respectively. Pyruvate is probably a major energy source for all early mammalian embryos.
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