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THE EFFECT OF PARA-INFLUENZA TYPE 1 (SENDAI) VIRUS INFECTION ON EARLY PREGNANCY IN THE RAT

Summary.: Infection of rats, 4 to 5 days pregnant, with aerosols of Sendai virus induced resorption of all embryos in nine out of the twelve animals examined.

Virus was recovered from the conceptus of only one of fourteen additional rats, although each was shown to have the agent in the lungs.

It is concluded that the observed termination of pregnancy is not due to virus growth within the cells of the conceptus, but is likely to be caused indirectly by the systemic upset in the pregnant animal induced by the respiratory disease.