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Journal of Reproduction and Fertility (1970) 23 243-247
DOI: 10.1530/jrf.0.0230243
Copyright © 1970 Society for Reproduction and Fertility
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INFLUENCE OF AN IUD ON THE LEUCOCYTIC CONTENT OF THE UTERUS AND ON THE DURATION OF PSEUDOPREGNANCY IN MICE

A. BARTKE

Summary.: Female mice had unilateral, silk thread IUDs removed 1, 2, 3 or 4 days after mating and were killed 1 to 5 days later. Histological sections of both uterine horns, or the uterine contents flushed out with water, were examined for the presence of leucocytes. Polymorphonuclear leucocytes which are invariably present in the lumen and endometrium of all horns containing an IUD and in a proportion of contralateral untreated horns, had usually disappeared in less than 48 hr after removing the IUD. This may explain the occurrence of implantations in mice from which the IUDs were removed 1 to 3 days after mating.

The duration of pseudopregnancy in mice with IUDs was increased and was more variable than in untreated mice.







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Copyright © 1970 by the Society for Reproduction and Fertility.