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There is some evidence that reserpine produces alteration of pituitary and testicular function in birds (Assenmacher, Tixier-Vidal & Baylé, 1961; Tixier-Vidal & Assenmacher, 1962). Hagen & Wallace (1960), working with cockerels, found that the testicular weight was reduced by half. However, very little is known about the effect of reserpine on the content of gonadotrophins in the pituitary of birds. The following experiment was conducted to investigate the total pituitary gonadotrophic potency in cockerels treated with reserpine.
The birds used were White Leghorn cockerels aged 100 days and weighing between 1·5 and 1·8 kg. They were kept on a lighting schedule of 14 hr light/10 hr dark and had free access to food and water. The reserpine (Serpasol, Ciba) was injected into the breast muscle at a
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