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IMMUNOLOGICAL ASPERMATOGENESIS IN MAN

Summary.: Corticosteroids were used in the treatment of a group of eighteen non-obstructive azoospermic or severely oligospermic patients showing a positive lymphocyte blastoid transformation test in response to a seminal antigen. A control group of eleven similarly affected patients with negative blastoid transformation tests was given the same treatment. Response was noticed in nine of the positive test group (50%), and one patient's wife conceived. None of the control group showed any response.

The value of this trial therapy is discussed.

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