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THE TIME OF OVULATION IN THE EWE FOLLOWING TREATMENT WITH HUMAN CHORIONIC GONADOTROPHIN

The object of the experiments described below was to estimate the time at which ovulation occurs in sheep treated with gonadotrophin and to provide, if possible, sheep oocytes of known age in connection with experiments on the hybridization of sheep and goats.

Ortavant, Thibault & Wintenberger (1949) found that ovulation occurred about 24 hr after the intravenous injection, given at the beginning of oestrus, of a mixture of pregnant mares' serum (PMSG) and human chorionic gonadotrophin (HCG). Braden, Lamond & Radford (1960) found that ovulation occurred between 20 and 28 hr after injection of HCG in ewes previously treated with progesterone and PMSG. In ewes previously treated with 6-methyl-17-acetoxyprogesterone, ovulation was found to occur 25 hr after injection of HCG (Dziuk, Hinds, Mansfield & Baker, 1964). Moor, Rowson, Hay & Caldwell