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STUDIES UPON THE MECHANISM OF RESERPINE-INDUCED ARREST OF EGG TRANSPORT IN THE MOUSE OVIDUCT

Summary.: The position of mouse eggs in the reproductive tract was determined following the administration of various doses of reserpine by the intraperitoneal route on Day 1 of pregnancy. High doses caused arrest of egg transport, while lower doses caused delay. The possibility that reduced hormone secretion is responsible was investigated by administration of ovarian, hypophysial and thyroid hormones. The failure of these various treatments to reverse the reserpine-induced arrest of egg transport suggests that alterations in hormone secretion are not the primary cause of the arrest.