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INTRODUCTION
I did not select the title of this particular presentation, but I must compliment those who did because, fortunately, it allows a considerable amount of latitude insofar as the subject matter is concerned. While the current researches I plan to discuss are rather diversified, they essentially have been built upon our early studies. Therefore, perhaps by way of introduction, it would be appropriate to discuss briefly the history of our clinical research programme in general.
Our Family Planning Centres in Los Angeles embarked on a programme of evaluation of simpler forms of contraception in the early 1950s. At that time, we were looked upon as `radicals' because we had the temerity to suggest that perhaps the diaphragm and jelly did not have to be the only effective medicallyprescribed method of contraception. We went so far as to suggest, and then demonstrate, that certain specially prepared creams and jellies
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