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GENETIC CONTENT AND BUOYANT DENSITY OF RABBIT SPERMATOZOA

The possibility of controlling the transmission of heritable characters by differential separation, inactivation or destruction of spermatozoa according to their individual genetic content depends on whether the phenotype of the developing or mature spermatozoon is affected by its own haploid genetic content. The present work shows no evidence of any such 'haploid effect' on the buoyant density of spermatozoa attributable to the segregation of three simple Mendelian factors (sex, albino and rex locus alleles) or to the segregation of factors determining viability of young at birth, and no certain effect among the various genes governing birth weight.

The living spermatozoa of whole single ejaculates were fractionated into different buoyant density classes by centrifugation to near-equilibrium after layering upon 4-ml dextran-based density gradients each covering a range of 0·02 specific gravity units