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Journal of Reproduction and Fertility (1969) 19 191-193
DOI: 10.1530/jrf.0.0190191
Copyright © 1969 Society for Reproduction and Fertility
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RELAXIN ACTIVITY DURING THE OESTROUS CYCLE OF THE MARSUPIAL, TRICHOSURUS VULPECULA (KERR)

C. H. TYNDALE-BISCOE

Relaxin has been assayed from a wide variety of vertebrates (Steinetz, Beach & Kroc, 1959; Hall, 1960) but its function is only known in a few eutherian mammals where it facilitates parturition through effects on the connective tissue of the genital tract and the pelvis. The highest concentrations of the hormone are found during the latter half of pregnancy in the ovaries, uteri and placentae. In some species, notably the rabbit (Marder & Money, 1944), relaxin also occurs in the peripheral blood in increasing amounts during pregnancy and falls abruptly after parturition.

In marsupials, the possibility that relaxin is important at parturition in facilitating passage of the foetus through the pseudo-vaginal passage has been investigated (Tyndale-Biscoe, 1966) and a relaxin-like activity was detected in the corpus luteum but not the




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