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Height measurements of surface and glandular epithelium, cell to nucleus length ratios and glandular lumen sizes have been employed for evaluating the endometrial activity of the uterus in the cow (Asdell, DeAlba & Roberts, 1948; Dziuk, Donker, Nichols & Peterson, 1958; Foley & Reece, 1948; Weeth & Herman, 1952; Johnson, 1965). These techniques, however, have not been completely satisfactory. For example, epithelial height measurements were reported to vary greatly in areas of tissue closely adjacent to one another (Dziuk et al., 1958). Johnson (1965) found that epithelial height varied between and within periods of the oestrous cycle to such an extent that this measurement was not valid for estimating the stage of the cycle.
Hultquist (1959) described a technique of karyometry used on β-cells of the
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