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Summary.: Closely related members of a homologous series of alkane sulphonic esters were administered to pregnant rats and their effect on oogenesis and fertility of female offspring studied. A marked antifertility action due to the diesters n = 1, 3, 4 and the branched chain monoester isopropyl methanesulphonate was referable to interference with oogonia. Methyl and ethyl monoesters also had an antifertility action although their effect was less evident.
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