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Journal of Reproduction and Fertility (1969) 18 15-20
DOI: 10.1530/jrf.0.0180015
Copyright © 1969 Society for Reproduction and Fertility
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EFFECT OF ALKANE SULPHONIC ESTERS ON OVARIAN DEVELOPMENT AND FUNCTION IN THE RAT

B. N. HEMSWORTH

Summary.: Closely related members of a homologous series of alkane sulphonic esters were administered to pregnant rats and their effect on oogenesis and fertility of female offspring studied. A marked antifertility action due to the diesters n = 1, 3, 4 and the branched chain monoester isopropyl methanesulphonate was referable to interference with oogonia. Methyl and ethyl monoesters also had an antifertility action although their effect was less evident.







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Copyright © 1969 by the Society for Reproduction and Fertility.