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Summary.: The intraluminal fluid from the rat uterus with an intrauterine silk thread suture exerts an anti-implantation effect when administered intraluminally into the uterus of a recipient rat on Day 2 and Day 4 but not on Day 6 of pregnancy. It is suggested that the intra-uterine device exerts its antifertility effect by release of a pharmacologically active agent.
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