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THE EFFECTS OF 22,25-DIAZACHOLESTEROL DIHYDROCHLORIDE ON THE PIGEON TESTIS AND ON REPRODUCTIVE BEHAVIOUR

In recent years, attention has been focused on the potential of reproduction inhibitors for the possible control of harmful birds (Davis, 1961, 1962; Elder, 1964; Becker, 1966). Elder, in his search for an effective avian oral contraceptive, found that the best results were obtained with a hypocholesterolemic agent, 22,25-diazacholesterol dihydrochloride (compound SC-12937, Searle & Co., Chicago). When this constituted 0·1% of the diet of pigeons for 10 days, ovulation was inhibited for 3 months and impaired for a further 3 to 9 months. The present study was designed to investigate the effects of compound SC-12937 on the pre-incubatory behaviour of Columba livia and to assess the action of the drug on normal testis cytology.

Males and females in two groups, each of

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				J. Sturtevant Pigeon Control by Chemosterilization: Population Model from Laboratory Results Science, October 16, 1970; 170(3955): 322 - 324. [Abstract] [PDF]