This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by PICKWORTH, S. Articles by LAMMING, G. E. Search for Related Content PubMed Articles by PICKWORTH, S. Articles by LAMMING, G. E.

OBSERVATIONS ON PREGNANCY IN INTACT RABBITS AND IN OVARIECTOMIZED RABBITS TREATED WITH 17HYDROXYPROGESTERONE CAPROATE

Summary.: Rabbits ovariectomized 24 hr post coitum (p.c.) were injected i.m. with 2 mg or 4 mg 17-hydroxyprogesterone caproate daily. Pre-natal development was compared with that of control litters at 9 and 29 days, 5 days and 7 days p.c. The 2 mg treatment supported 26·4% pre-natal survival to 29 days p.c., most mortality occurring between 7 and 9 days. The 4 mg dose rate permitted 71 ·0% survival to 29 days p.c. which was not significantly different from controls (81·5%). Blastocyst size at 5 days p.c. was not significantly affected by treatment but both ovariectomized groups showed slight retardation at 7 days when stage of attachment was assessed by observation and by analysis of blastocyst fluid for lactic acid. Attachment was least advanced in the group receiving the lower dose rate.

In 29-day foetuses the degree of ossification of the femur was positively related to foetus weight. In control litters deposition of calcium and total ash components and relative decrease in water content were also further advanced in the larger foetuses, suggesting a general association of size and maturity.

This article has been cited by other articles:

				K.B.C. Apparao, M. J. Illera, S. A. Beyler, G. E. Olson, K. G. Osteen, M. H. Corjay, K. Boggess, and B. A. Lessey Regulated Expression of Osteopontin in the Peri-Implantation Rabbit Uterus Biol Reprod, May 1, 2003; 68(5): 1484 - 1490. [Abstract] [Full Text] [PDF]