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STUDIES OF EFFECTS OF t-ALLELES IN THE HOUSE MOUSE ON SPERMATOZOA

Summary.: Males bearing certain combinations of alleles at locus T (linkage group IX in the house mouse) have been tested and shown to be mating-sterile. The numbers, motility and location of spermatozoa of such males have been examined in the reproductive tracts of females inseminated by them. Similar observations on the spermatozoa of fertile males bearing other combinations of t-alleles served as controls. The observations indicate that this genotypic sterility is related not to numbers of spermatozoa entering the female tract but to lowered motility which results in their failure to remain near the site of fertilization.