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Molecular genetic approaches to studying fertilization in model systems

Waksman Institute, Rutgers University, Piscataway, New Jersey 08854, USA

Correspondence should be addressed to A Singson; Email: Singson{at}waksman.rutgers.edu

In a wide range of experimental systems, a variety of both forward and reverse genetic approaches are becoming available for the study of the molecules involved in fertilization. An integration of these methods with the antibody-based and biochemical studies traditionally used in fertilization research is enabling rapid advancements in our understanding of this process. We highlight some of the recent advances resulting from these genetic methods and their applications in these systems.

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