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THE INCIDENCE OF SPONTANEOUS DECIDUOMATA IN PSEUDOPROPREGNANT RATS

In the pseudopregnant rat, deciduomata have been generally produced by surgical or chemical trauma of the uterus. The optimal administration time for these stimuli was found to be Day 4 of pseudopregnancy, and maximal decidual responses were obtained 5 days later (De Feo, 1963a). However, we have observed that deciduomata developed spontaneously in the absence of uterine trauma, and attempted to determine its frequency.

Wistar-strain, female rats obtained from the Royal Hart colony, and weighing approximately 250 g, were used. They were housed in a controlled illumination environment of 14 hr light and 10 hr darkness, and were maintained on unlimited Purina Chow and water. During oestrus, the animals were made pseudopregnant by cervical stimulation with a glass rod or matings with vasectomized males. Day 1 of pseudopregnancy