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THE EFFECT OF ANAESTHESIA ON ENDOCRINE RESPONSES TO OLFACTORY STIMULI IN FEMALE MICE

Summary.: The incidence of the Bruce effect (block of pregnancy in newly-mated female mice exposed to the smell of male mice of another strain) is significantly lowered in mice anaesthetized with `Avertin' (tri-bromethanol and amylene hydrate) 10 to 12 days before mating. Pentobarbitone anaesthesia may have a similar effect. `Avertin', but not pentobarbitone anaesthesia, also prevents the appearance of the Whitten effect. The use of `Avertin' in the investigation of neuro-endocrine effects involving the olfactory system is not advisable.